Recently, running windows applications without running it for a while left me with error as follows: (noted down for better reference for search engine.)

wine_line_error

Window title: Themida

Message:

A debugger has been found running in your system.
Please, unload it from memory and restart your program.

The root cause is the kernel parameter kernel.yama.ptrace_scope.

Users may want to harden their system and set this value to higher than default 1. Thus cause the trigger.

Read Arch Wiki/Security/ptrace_scope for more details.

!!Use 1 for wine!!